Dr. ILANA KOLODKIN-GAL
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PhD (Summa cum laude)- Hebrew University of Jerusalem Awarded 2009
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Post-doctoral fellowship- Harvard University (EMBO fellow, HFSP fellow) 2009-2013
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Senior Scientist, Weizmann Institute of Science 2013-2021, Publications ,Lab members ,Research
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Current Affiliation: https://plantpathology.agri.huji.ac.il/
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Contact: Ilana.kolodkin@mail.huji.ac.il
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Follow me on twitter at @ikgbiofilms
ORCID
https://orcid.org/0000-0002-8464-5660
Loop profile
Expertise. Understanding bacterial multicellular communities, such as biofilms. This field is highly significant from clinical, agricultural and ecological perspectives, e.g, biofilms formed by various pathogens play a critical role in device-related infections, dental infections, acute septic arthritis and plant diseases. On the same time, biofilms formed by beneficial bacteria can also be highly beneficial for maintaining the diversity of natural habitats.
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Kolodkin-Gal I., Hazan R., Gaathon A., Carmeli S. and Engelberg-Kulka H. A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli. Science (318):652-655, doi:10.1126/science.1147248 (2007). https://www.science.org/doi/10.1126/science.1147248?url_ver=Z39.88-2003
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Kolodkin-Gal I#., Alexander Helholz#, Kolter R., and Losick R. Respiration control of multicellularity in Bacillus subtilis by a complex of the cytochrome chain with a membrane-embedded histidine kinase. Genes & Development (27):887-899, doi:10.1101/gad.215244.113 (2013). http://genesdev.cshlp.org/content/27/8/887.full.pdf+html
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Steinberg N#, Keren-Paz A#, Hou Q., Doron S., Yanuka-Golub K., Olender T., Hadar R., Rosenberg G., Jain R., , Cámara-Almirón J., Romero d., Van Teefelen S., and Kolodkin-Gal I$. An extracellular matrix protein serves as a developmental cue to maintain a motile subpopulation within biofilms. Science Signaling. (2020), https://www.science.org/doi/10.1126/scisignal.aaw8905
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Maan H., Itkin, M., Malitsky, S. Friedman J. and Kolodkin-Gal I$. Resolving the conflict between antibiotic production and rapid growth by recognition of peptidoglycan of susceptible competitors. Nature Communications (2022) https://www.nature.com/articles/s41467-021-27904-2
Bacteria - Having Their Fortress and Leaving It Too: Motile cells move forward during engulfment, followed by matrix producers